With
aging, white matter hyperintensities often develop in the brain, with
these small areas of damage potentially affecting movement abilities –
such as walking independently. Debra A. Fleischman, from Rush
University Medical Center (Illinois, USA), and colleagues enrolled 167
men and women, average age 80 years, to wear movement monitors on
their wrists for up to 11 days to measure exercise and non-exercise
activity. Movement abilities were assessed via standardized tests, and
volume of white matter hyperintensities in the brain was determined via
magnetic resonance imaging (MRI). The team found that the subjects in
the top 10% in activity level (as measured via movement monitors)
experienced activity equal to walking at 2.5 mph for an additional 1.5
hours each day (as compared to those at 50th percent activity level);
having greater amounts of brain damage did not change their scores on
the movement tests. However, among those at the 50th percent activity
level, having greater amounts of brain damage did associate with
significantly lower scores on the movement tests. Observing that:
“higher [white matter hyperintensity] burden remained associated with
lower motor function in persons with average (50th percentile) activity,
the study authors write that: “Higher levels of physical activity may
reduce the effect of [white matter hyperintensity] burden on motor
function in healthy older adults.”
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